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Cmax, AUC, Vd, T1/2, WTF??

Practical tips on when and how to use pharmacokinetics when using veterinary drugs

Approved for 1.5 of ABVMA CE Credit

Most veterinarians have some familiarity with basic pharmacokinetic (PK) principles.  However, pharmacokinetics can be quite complex and difficult to interpret.  It is easy for veterinarians to misinterpret PK information, or more commonly, incorrectly apply this information when using veterinary drugs.  This presentation will have three main objectives:

  1. To briefly review the basic PK principles of relevance to veterinarians

  2. To demonstrate clinical scenarios in which PK principles are applicable and helpful when using veterinary drugs 

  3. Most importantly, to understand the limitations of PK applications when selecting veterinary drugs.  Specific examples of misleading recommendations based on an inappropriate application of pharmacokinetics will be highlighted. 

 

Alan Chicoine DVM, MSc, Diplomate ACVCP (American College of  Veterinary Clinical Pharmacology)

 

Dr. Chicoine graduated from the Western College of Veterinary Medicine (WCVM) in 2003. He worked in a mixed animal practice for 2 years before starting a graduate program and clinical pharmacology residency at the WCVM in 2005.  In 2007 he completed his MSc and passed his American College of Veterinary Clinical Pharmacology board exams.  

 

Dr. Chicoine has been with the Department of Veterinary Biomedical Sciences at the WCVM since 2007 in the role of Assistant Professor.  During this time he also worked as a drug evaluator for the Clinical Evaluation and Human Safety Divisions of Health Canada’s Veterinary Drugs Directorate.  His primary teaching duties include pharmacology and physiology courses for undergraduate veterinary students, and his research interests include drug residues in food animals, clinical pharmacokinetics, and antimicrobial resistance issues.

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